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br Proposed methodology At the outset the wind power
2021-08-06
Proposed methodology At the outset, the wind power outputs must be obtained which are to be included in the OPF model. This work utilizes a modified version of the simulation method. Rather than using the simulated wind power values for each hour of the year, the probability of each wind power in
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After the policy of the current British Commonwealth countri
2021-08-05
After 1915, the policy of the (current) British Commonwealth countries (including Britain, Canada, Australia, India, New Zealand and South Africa) regarding the dead, was to ensure that as far as possible, whether identified or not, all recovered bodies would be given individual graves, with standar
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Prostaglandin E receptor subtype EP is a transmembrane G
2021-08-05
Prostaglandin E receptor subtype 4 (EP4) is a transmembrane G-coupled protein receptor activated by prostaglandin E2 (PGE2). EP4 activation exerts anti-inflammatory effects in adipose tissue by dampening the levels of inflammatory chemokines [12]. In the mouse, EP4 deficiency aggravates fragmentatio
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Many studies have documented that enolase acts as a
2021-08-05
Many studies have documented that enolase acts as a plasminogen-binding protein and this interaction is involved in the tissue invasion and pathogenicity of the causative agents (Almeida et al., 2004; Avilan et al., 2000; Marcilla et al., 2007; Mundodi et al., 2008; Vanegas et al., 2007). Furthermor
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Recently a non proteolytic role of COP in
2021-08-05
Recently, a non-proteolytic role of COP1 in stabilizing PIF3 proteins in the dark has been revealed . Previous studies have shown that the endogenous levels of PIF3 protein in etiolated seedlings were nearly undetectable . Ling found that the GSK3-like kinase BRASSINOSTEROID-INSENSITIVE 2 (BIN2) pla
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Several studies have indicated that ICT induces activation
2021-08-05
Several studies have indicated that ICT induces activation of ERK and p38 kinase in a variety of cells. The ERK pathway was involved in and partly contributed to the neuroprotective effects in rat neuronal nrf2 keap1 [14] and anticancer effects in several cancer cells [5], [7], [8]. ICT could also
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PF-670462 The authors identified inhibitors of SUMOylation u
2021-08-05
The authors identified inhibitors of SUMOylation using two assays to monitor the conjugation of SUMO1 to RanGAP1 by E1 and E2 enzymes: a fluorescence resonance energy transfer (FRET) primary screen that evaluated over 250,000 compounds and a chemiluminescence secondary screen. A counter screen was u
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In a study carried out by Aunis et
2021-08-05
In a study carried out by Aunis et al. the properties of soluble DBH and membrane bound were examined [23]. The membrane bound enzyme was shown in colony stimulating factor 1 receptor to the soluble form to have thermal denaturation at higher temperatures of 43.5–44°C. Similar discontinuities in th
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Recent studies have shown arsenic
2021-08-05
Recent studies have shown arsenic could cause autophagic cell death in malignant cells, including leukemia and malignant glioma Tarafenacin [16], [17]. However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its related proteins
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Interestingly global EGFR depletion increased the rate of ce
2021-08-04
Interestingly, global EGFR depletion increased the rate of cell elimination everywhere in the notum (Figures 2B–2D), irrespective of the deformation status of the cells. Accordingly, we found that chemical d are not any more sensitive to stretching upon EGFR depletion (Figures S6A–S6C; Video S5). T
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pkc inhibitor The underlying assumption of consolidation re
2021-08-04
The underlying assumption of consolidation/re-consolidation is that the pkc inhibitor activity initiated during the acquisition trial/re-consolidation trial continues to persist briefly after completion of the trial and it is during this post-trial period that immediate post-trial treatments can in
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In summary EP signaling modulates
2021-08-04
In summary, EP1 signaling modulates heteromeric kainate receptors at multiple steps, both sensitizing mice to kainate-evoked status epilepticus and, separately, exacerbating the downstream consequences of status epilepticus. These results, together with those of Serrano et al. (2011) and Jiang et al
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The importance of AAE in enhancing the survival of plants
2021-08-04
The importance of AAE3 in enhancing the survival of plants and yeast when confronted with certain environmental stresses has been documented in recent reports. In response to biotic stress such as oxalate-secreting micro-organisms, AAE3 was found to reduce the inhibitory growth effects of the secre
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DHODH activity has been traditionally
2021-08-04
DHODH activity has been traditionally measured with the standard colorimetric assay that monitors 2,6-dichloroindophenol (DCIP) reduction as absorbance decrease at 600 nm . This assay has permitted the identification of several families of DHODH inhibitors in a successful high-throughput screening (
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br The contribution of Interference RNA and epigenetic in OA
2021-08-03
The contribution of Interference RNA and epigenetic in OA attenuation Interference RNA, a cellular mechanism for post-transcriptional gene silencing that is associated with mRNA. The potential of RNAi has successfully silenced the wide range of protein coding genes. Its high specificity sanctions
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